Work information

Title The COHERENT model (Clinical Outcomes, HEalthcare REsource utilizatioN, and relaTed costs)
The COHERENT model (Clinical Outcomes, HEalthcare REsource utilizatioN and relaTed costs) is a technological framework designed to integrate the analysis of clinical outcomes, healthcare resource utilization, and the economic costs associated with different diseases. Its primary objective is to offer a comprehensive and comparative perspective of both patient clinical trajectories and the economic burden generated by a disease. This enables the identification of care patterns, healthcare workload, and opportunities for improvement in health system management. The model integrates multiple hospital data sources and structures the information in a reproducible and standardized manner, facilitating its application in research as well as in the planning and evaluation of health policies.
The model has currently been validated for use in heart failure (HF) and chronic obstructive pulmonary disease (COPD), and its development is supported by numerous publications in scientific journals:

• Héctor Bueno, José L. Bernal, Víctor Jiménez-Jiménez, Francisco Javier Martín-Sánchez, Xavier Rossello, Guillermo Moreno, Clara Goñi, Víctor Gil, Pere Llorens, Nerea Naranjo, Javier Jacob, Pablo Herrero-Puente, Sergio Garrote, Juan Carlos Silla-Castro, Stuart J. Pocock, Òscar Miró; The Clinical Outcomes, Healthcare Resource Utilization, and Related Costs (COHERENT) Model: Application in Heart Failure Patients. Revista Española de Cardiología (English Edition). 2022;75(7):585-594. DOI: 10.1016/j.rec.2021.08.009.

• Héctor Bueno, Clara Goñi, Rafael Salguero-Bodes, Beatriz Palacios, Lourdes Vicent, Guillermo Moreno, Nicolás Rosillo, Luis Varela, Margarita Capel, Juan Delgado, Fernando Arribas, Manuel del Oro, Carmen Ortega, José L. Bernal; Primary vs. Secondary Heart Failure Diagnosis: Differences in Clinical Outcomes, Healthcare Resource Utilization, and Cost. Frontiers in Cardiovascular Medicine. 2022;9. DOI: 10.3389/fcvm.2022.818525.

• Juan C. López-Azor, Juan F. Delgado, Jorge Vélez, Rocío Rodríguez, Jorge Solís, Manuel del Oro, Carmen Ortega, Rafael Salguero-Bodes, Beatriz Palacios, Lourdes Vicent, Guillermo Moreno, Nicolás Rosillo, Luis Varela, Margarita Capel, Fernando Arribas, José L. Bernal, Héctor Bueno; Differences in Clinical Outcomes, Healthcare Resource Utilization, and Costs in Heart Failure Patients According to Left Ventricular Ejection Fraction. Revista Española de Cardiología (English Edition). 2023;76(11):862-871. DOI: 10.1016/j.rec.2023.06.003.

• Carlos J. Alvarez-Martinez, Jorge Vélez, Clara Goñi, Joaquín Sánchez-Covisa, Mónica Juárez-Campo, Luciano Escudero, José L. Bernal, Nicolás Rosillo, Miguel Hernández, Héctor Bueno; Application of the Clinical Outcomes, Healthcare Resource Utilization, and Related Costs Model in Chronic Obstructive Pulmonary Disease Patients. Respiration. 2024. DOI: 10.1159/000541406.

• Martín Romo, Claudia Yuste, Jorge Vélez, Miguel Hernández, Beatriz Palacios, Raquel Pita, Margarita Capel, Sandra Fernández Fernández, Nicolás Rosillo, Guillermo Moreno, Manuel Del Oro, Carmen Ortega, José L. Bernal, Héctor Bueno; Clinical outcomes, health care resource utilization and costs by renal function in patients with heart failure. Revista Española de Cardiología. 2025. DOI: 10.1016/j.rec.2025.08.005. PMID: 40976501

• Carlos J. Alvarez-Martinez, Miguel Hernández, Jorge Vélez, Joaquín Sánchez-Covisa, Juan Moreno-González, Luciano Escudero, Nicolás Rosillo, Diego Alvaredo, Guillermo Moreno, Manuel del Oro, Carmen Ortega, José L. Bernal, Héctor Bueno; Clinical and economic impact of concomitant heart failure in patients with exacerbated COPD. Respiratory Medicine. 2025 Nov;248:108381. doi: 10.1016/j.rmed.2025.108381. Epub 2025 Sep 25. PMID: 41015398.
Work type Unclassified
Tags resource utilization, value-based medicine, analytical visualization, composite outcomes, coherent model, costs

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Registry info in Safe Creative

Identifier 2512154022435
Entry date Dec 15, 2025, 7:33 AM UTC
License Creative Commons Attribution-NonCommercial-ShareAlike 4.0

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Copyright registered declarations

All exploitation rights 50.00 %. Holder Fundación Investigación Biomédica Hospital 12 de Octubre. Date Dec 15, 2025. From Jan 1, 2025. Geographic coverage: Mundial.
Author 66.00 %. Holder Héctor Bueno. Date Dec 15, 2025.
Author 12.00 %. Holder Jose Luis Bernal Sobrino. Date Dec 15, 2025.
Author 10.00 %. Holder Jorge Vélez García. Date Dec 15, 2025.
Author 8.00 %. Holder Guillermo Moreno Muñoz. Date Dec 15, 2025.
Author 3.00 %. Holder Miguel Hernández Gómez. Date Dec 15, 2025.
Author 1.00 %. Holder Nicolás Rosillo Ramírez. Date Dec 15, 2025.
All exploitation rights 50.00 %. Holder Centro Nacional de Investigaciones Cardiovasculares (CNIC). Date Dec 15, 2025. From Jan 1, 2025. Geographic coverage: Mundial.


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