Dante is a small poison dart frog, a member of the terribilis species known for its toxic skin. He is part of a scientific study conducted aboard an airborne laboratory on a plane. One day, during a research flight, Dante is exposed outside the aircraft as scientists have discovered that his skin venom, when in contact with clouds, can trigger rain through an electrical reaction. However, something goes wrong, and Dante falls into a pond in the midst of the jungle, precisely in a small community of insects. There, he faces rejection for being different and dangerous to the local inhabitants.
Later, a massive forest fire breaks out, and it turns out that Dante's venom may be the only solution to extinguish this raging blaze threatening life in the jungle.
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